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Module 1 · General Principles of Pharmacology · Course 04 of 5
Pharmacogenomics & Therapeutic Drug Monitoring
- Course 4 of 5
- 24 lessons
- 5 Quick Recall Checks
- 2 final assessments
- Free in Module 1
Study how genetic variation and measured drug concentrations inform individualized therapy. Practice interpreting these results alongside patient factors, treatment response and toxicity risk.
Role in Module 1: Examines interindividual variability and the interpretation of genetic results and measured drug concentrations. Recommended after Pharmacodynamics. How the five courses fit together →
Syllabus
Course syllabus and recall checkpoints
The full lesson list, grouped by the Quick Recall Check that closes each unit.
Unit 1Individualized Therapy and PGx Foundations6 lessons
- 1Introduction to Individualized Therapy and Precision Pharmacology
- 2Why Patients Respond Differently
- 3PK Variability vs PD Variability
- 4Clinical Reasoning Framework for Individualized Therapy
- 5Basic Human Genetics for Clinical Pharmacology
- 6Genotype, Diplotype, Haplotype, and Phenotype
Smart Drill checkpoint · Quick Recall Check 1
Unit 2Functional Variation and PGx Prescribing6 lessons
- 7Functional Variation: Loss, Gain, and Altered Function
- 8Metabolizer Phenotypes
- 9Pharmacogenomics in Pharmacokinetics
- 10Pharmacogenomics and Precision Pharmacodynamics
- 11CYP Examples That Change Prescribing
- 12Transporter, Enzyme, and Toxicity PGx Beyond CYP
Smart Drill checkpoint · Quick Recall Check 2
Unit 3Actionability, HLA, and Clinical Decisions4 lessons
- 13HLA-Associated Toxicity and Immune Risk
- 14When PGx Changes Prescribing Decisions
- 15Interpreting Pharmacogenomic Reports
- 16Limitations: Avoiding Genetic Determinism
Smart Drill checkpoint · Quick Recall Check 3
Unit 4Therapeutic Drug Monitoring Fundamentals4 lessons
- 17Therapeutic Drug Monitoring: Why Measure Concentrations?
- 18Therapeutic Window, Target Concentration, and Clinical Endpoint
- 19TDM Sampling: Timing Is Everything
- 20Free vs Total Concentrations and Protein Binding
Smart Drill checkpoint · Quick Recall Check 4
Unit 5Precision Dosing and PGx/TDM Integration4 lessons
- 21TDM Calculations and Dose Revision
- 22Nonlinear PK and High-Risk TDM
- 23Modern TDM: AUC and Bayesian Dosing
- 24Precision Dosing Algorithm: Integrating PGx and TDM
Smart Drill checkpoint · Quick Recall Check 5
Course Recall: Comprehensive Theory & Reasoning Assessment · Clinical Application & Mastery Assessment
How you’ll study
Apply pharmacology concepts and review your reasoning
- Study a pharmacology conceptUse focused lessons to develop your conceptual foundation.
- Recall and apply in a Smart DrillPractice retrieval and clinical application, then review immediate scoring and explanatory feedback.
- Target gaps and reassessUse feedback and AI Tutor review to identify reasoning gaps, repeat relevant practice and check your understanding.
Module 1 · General Principles of Pharmacology
Continue the Module 1 foundation
Course 01 · Free
Introduction to Clinical Pharmacology
Connect drug mechanisms, patient factors and evidence to therapeutic benefit–risk assessment.
17 lessons · 4 recall checks · 2 final assessments
Course 02 · Free
Pharmacokinetics
Apply absorption, distribution, metabolism and excretion to dosing and monitoring decisions.
67 lessons · 11 recall checks · 2 final assessments
Course 03 · Free
Pharmacodynamics
Interpret drug–target interactions and dose–response relationships to assess therapeutic benefit and adverse effects.
44 lessons · 5 recall checks · 2 final assessments
Course 05 · Free
Medication Safety, Adverse Reactions & Pharmacovigilance
Practice recognizing, assessing and reporting medication-related harm.
28 lessons · 5 recall checks · 2 final assessments
Start this course free.
Included in Module 1. No credit card required.