Autonomic Nervous System – Cholinergics

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Slide 1: Clinical Pharmacology of the Cholinergic System
Explore the clinical pharmacology of cholinergic drugs, from receptor signaling and therapeutic uses to adverse effects, toxicity, and safe patient care.

Course Content

01. Clinical Pharmacology of the Cholinergic System
02. The Core Prediction Rule
03. Autonomic Wiring Map
04. Acetylcholine Life Cycle
05. Pharmacologic Targets in ACh Signaling
06. Cholinergic Receptor Families
07. Muscarinic Signal Transduction
08. Tertiary vs Quaternary Amines
09. Muscarinic Activation by Organ
10. Endothelial M3–NO Paradox
11. Cholinergic Drug Classification
12. Direct Muscarinic Agonists
13. Bethanechol
14. Pilocarpine and Cevimeline
15. Carbachol and Methacholine
16. Practice: Direct Agonist Reasoning
17. AChE Inhibitors: Core Logic
18. Peripheral Reversible AChE Inhibitors
19. Myasthenia Gravis: Pharmacologic Logic
20. Myasthenic vs Cholinergic Crisis
21. CNS AChE Inhibitors in Dementia
22. Nicotinic Pharmacology
23. Irreversible AChE Inhibitors
24. Cholinergic Toxidrome
25. Nicotinic and CNS Toxicity
26. Organophosphate Management
27. Practice: Farmworker With Secretions
28. Muscarinic Antagonists: Core Effects
29. Atropine
30. Scopolamine
31. Inhaled Antimuscarinics
32. Ophthalmic Antimuscarinics
33. GU Antimuscarinics
34. CNS, GI, and Secretion Uses
35. Anticholinergic Toxidrome
36. Anticholinergic Toxicity Management
37. Ganglionic Blockers and Tone Logic
38. Mixed Differential Practice
39. Final High-Yield Synthesis
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